T.J. Lakis Mountziaris, a professor in the Chemical Engineering Department, will be the Distinguished Seminar Speaker for the Chemical Engineering Department at Northeastern University in Boston on January 28. Mountziaris will be speaking on “Synthesis, Functionalization and Biological Sensing Applications of ZnSe Nanocrystals” at 312 Ell Hall on the Northeastern campus from 11:45 a.m. to 1:00 p.m. on January 28. Read seminar announcement.
Professor Mountziaris earned a diploma in Chemical Engineering with highest honors from the Aristotle University of Thessaloniki, Greece, and a Ph.D. in Chemical Engineering from Princeton. After completing postdoctoral study in Chemical Engineering & Materials Science at the University of Minnesota, he started his academic career at the University at Buffalo in 1989.
He served as Program Director for Particulate and Multiphase Processes at the National Science Foundation before joining the Chemical Engineering Department at UMass Amherst as a professor and department head in 2005. Under his leadership the Chemical Engineering Department reached historical highs in faculty size, student enrollment, research expenditures, and gift income. He has presented numerous invited plenary talks at international conferences and is the recipient of several honors and awards, including the Norman Hackerman Award of the Electrochemical Society, The Chancellor’s Award for Excellence in Teaching of the SUNY system, and a Guest Professorship in Process Engineering from ETH-Zürich. Two of his U.S. patents on template-assisted synthesis of semiconductor nanocrystals have been licensed by a startup company.
As the abstract of the talk explains, “Nanocrystals of II-VI compound semiconductors, such as CdSe and ZnSe, have unique properties, including size-tunable photoluminescence, narrow emission and broad absorption spectra, high quantum yields, large extinction coefficients, and excellent photochemical stability. These materials are being studied as potential candidates for a wide range of novel applications in medical diagnostics, display technologies and solar energy conversion. ZnSe nanocrystals are particularly attractive, because they do not contain toxic heavy metal ions, such as Cd2+, and can be easily doped with transition metal ions, such as Mn2+ and Cu2+, thus providing additional control over their electronic properties. A novel technique that employs microemulsions and liquid crystals as templates for controlling the size and shape of ZnSe nanocrystals has been developed. Stochastic simulations of the process have revealed the underlying mechanisms of particle nucleation and growth while density functional theory calculations have provided insights on doping mechanisms. Extraction of the nanocrystals from the growth media and functionalization of their surface with organic molecules enables their stabilization in aqueous solutions and conjugation with biomolecules for applications in medical diagnostics. A new class of optical biosensors has been developed based on changes in the fluorescence emission spectra of ZnSe nanocrystals conjugated to biomolecular probes that are induced by the binding of the probes to target biomolecules. Detection of single-base DNA mutations and separation-free assays that enable rapid quantitative detection of proteins in solution will be discussed. The new biosensors are suitable for lab-on-a-chip portable devices that can provide rapid multiplexed detection of biological targets for point of care diagnostics.” (January 2015)